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The single active X in human cells: evolutionary tinkering personified

Barbara R Migeon1

  • 1McKusick Nathans Institute of Genetic Medicine, The Johns Hopkins University, 459 Broadway Research Building, 733 N Broadway, Baltimore, MD 21205, USA. bmigeon@jhmi.edu

Human Genetics
|June 10, 2011
PubMed
Summary

Mammals utilize X dosage compensation to equalize X chromosome expression between sexes. Evolutionary variations exist in this process, with the active X chromosome being randomly chosen early on.

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