Related Experiment Video
Updated: Jun 1, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
[72-year-old man with syncope and left hemiparesis].
C Weiss1, C Neumeier, F Siclari
1Abteilung für Innere Medizin, Gesundheitszentrum Unterengadin, Scuol, Switzerland. christoph.weiss@cseb.ch
A painless aortic dissection mimicking a stroke presented with neurological symptoms. Prompt diagnosis and surgical intervention were crucial to avoid fatal outcomes from misdirected thrombolytic therapy.
Area of Science:
- Cardiology
- Neurology
- Vascular Surgery
Background:
- Acute aortic dissection is a life-threatening condition often presenting with severe chest or back pain.
- Neurological deficits can occur but are typically associated with specific dissection types or complications.
Observation:
- A 72-year-old man presented with left hemiparesis and syncope, initially suspected as ischemic stroke.
- Clinical examination revealed pulse deficits and unmeasurable blood pressure in the left arm.
- Cranial computed tomography showed no acute abnormalities.
Findings:
- The patient was diagnosed with acute aortic dissection originating in the ascending aorta and extending to the iliac arteries.
- The dissection presented solely with neurological symptoms, complicating the initial diagnosis.
Implications:
- Painless aortic dissection with isolated neurological symptoms poses a significant diagnostic challenge.
- Misdiagnosis could lead to inappropriate thrombolytic therapy for stroke, with potentially fatal consequences.
- Early recognition and surgical management are critical for favorable outcomes in such atypical presentations.
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Hemorrhagic Stroke ll: Pathophysiology
Transient Ischemic Attack l: Introduction
Dementia l: Introduction
Hepatic Encephalopathy
Heart Failure III: Clinical Manifestations
![Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58641.jpg&w=3840&q=50)