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Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
Size-optimized 32-channel brain arrays for 3 T pediatric imaging
Boris Keil1, Vijay Alagappan, Azma Mareyam
1Department of Radiology, Massachusetts General Hospital, AA Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA. keil@nmr.mgh.harvard.edu
Magnetic Resonance in Medicine
|June 10, 2011
Summary
New pediatric brain MRI coils, optimized for five age groups, significantly boost signal-to-noise ratio. This size-tailored approach enhances imaging quality for children, improving diagnostic accuracy.
Area of Science:
- Medical Imaging
- Biomedical Engineering
- Radiology
Background:
- Pediatric brain imaging requires specialized coils for optimal signal acquisition.
- Existing adult coils and generic pediatric coils may not provide adequate sensitivity for young patients.
- Accelerated imaging techniques in pediatric MRI necessitate high signal-to-noise ratio (SNR) performance.
Purpose of the Study:
- To develop and evaluate size-optimized 32-channel receive array coils for pediatric brain imaging across five distinct age groups.
- To compare the performance of these novel pediatric coils against standard adult and pediatric coils.
- To assess the impact of size optimization on signal-to-noise ratio and parallel imaging performance.
Main Methods:
- Development of five distinct 32-channel array coils tailored to neonates, 6-month-olds, 1-year-olds, 4-year-olds, and 7-year-olds.
- Coil formers were designed using 3D MRI data to match the specific head contours of each age group.
- Evaluation involved phantom measurements comparing SNR and noise amplification for parallel imaging against a commercial adult coil and a pediatric birdcage coil.
Main Results:
- The developed pediatric coils demonstrated significant SNR increases across all brain regions compared to the adult and birdcage coils.
- SNR improvements in the brain cortex ranged from 1.7-fold to 3.6-fold, depending on the age group, relative to the adult coil.
- Enhanced G-factor maps indicated improved performance for accelerated imaging protocols with the pediatric-specific coils.
Conclusions:
- Size-optimized, age-tailored 32-channel array coils significantly enhance SNR for pediatric brain MRI.
- This approach offers substantial sensitivity gains, benefiting both accelerated and conventional pediatric brain imaging.
- Custom-fit coil technology is crucial for advancing the quality and efficiency of pediatric neuroimaging.

