[The combined therapy of patients with severe craniocerebral injury]

The hemostasis system was studied in 423 patients. Coagulation occurred in a definite sequence: its expressiveness and duration were determined by the severity and form of brain damage. In the period of hypercoagulative changes (from 2 to 15 days and longer), thrombotic processes were revealed in 16% of the cases. Anticoagulative treatment including heparin, indirect anticoagulants, des- and antiaggregates, as well as fibrinolytics were applied in 27% of the cases, which reduced mortality by 12%.