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Related Experiment Video

Updated: Jun 1, 2026

Synthesis, Assembly, and Characterization of Monolayer Protected Gold Nanoparticle Films for Protein Monolayer Electrochemistry
14:18

Synthesis, Assembly, and Characterization of Monolayer Protected Gold Nanoparticle Films for Protein Monolayer Electrochemistry

Published on: October 4, 2011

CPMV-polyelectrolyte-templated gold nanoparticles.

Alaa A A Aljabali1, George P Lomonossoff, David J Evans

  • 1Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, United Kingdom.

Biomacromolecules
|June 11, 2011
PubMed
Summary
This summary is machine-generated.

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This study demonstrates using polyelectrolyte-coated Cowpea mosaic virus (CPMV) to create uniform gold nanoparticles. The virus template facilitates gold nanoparticle synthesis and self-assembly into complex structures.

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biotechnology

Background:

  • Cowpea mosaic virus (CPMV) can serve as a biological scaffold.
  • Surface modification of viral capsids is a strategy for nanomaterial synthesis.

Purpose of the Study:

  • To describe the templated synthesis of gold nanoparticles using polyelectrolyte-modified CPMV.
  • To investigate the self-assembly of preformed gold nanoparticles on modified CPMV.

Main Methods:

  • Electrostatic binding of poly(allylamine) hydrochloride (PAH) to CPMV.
  • Templated synthesis of gold nanoparticles via reduction of adsorbed gold complexes.
  • Self-assembly of preformed gold nanoparticles onto CPMV-PA.

Main Results:

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Last Updated: Jun 1, 2026

Synthesis, Assembly, and Characterization of Monolayer Protected Gold Nanoparticle Films for Protein Monolayer Electrochemistry
14:18

Synthesis, Assembly, and Characterization of Monolayer Protected Gold Nanoparticle Films for Protein Monolayer Electrochemistry

Published on: October 4, 2011

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
10:38

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Published on: January 15, 2018

Gold Nanoparticle Synthesis
13:42

Gold Nanoparticle Synthesis

Published on: July 10, 2021

  • Narrowly dispersed gold nanoparticles were synthesized on the PAH-CPMV surface.
  • The synthesized gold nanoparticles can be further functionalized with thiol reagents.
  • CPMV-PA induced self-assembly of preformed gold nanoparticles into hexagonal spheres.

Conclusions:

  • Polyelectrolyte-modified CPMV is effective for templated gold nanoparticle synthesis.
  • CPMV-PA acts as a template for the ordered assembly of gold nanoparticles.