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A highly efficient type I β-turn mimetic simulating an Asx-Pro-turn-like structure.

Andrea Pinsker1, Jürgen Einsiedel, Steffen Härterich

  • 1Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich Alexander University, Schuhstrasse 19, 91052 Erlangen, Germany.

Organic Letters
|June 11, 2011
PubMed
Summary

Researchers developed novel peptide mimetics simulating type I β-turns using ring-closing olefin metathesis. These Asx-Pro-turn mimetics offer stable U-turn conformations, advancing peptide structure research.

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