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Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

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Optical modulation of molecular conductance.

Shreya Battacharyya¹, Ashley Kibel, Gerdenis Kodis

¹Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona 85287, United States.

|June 11, 2011

Summary

Illuminated porphyrin-fullerene molecules showed increased conductance, suggesting a long-lived charge separated state. This finding aids in designing molecular photovoltaic devices.

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Area of Science:

Molecular electronics
Photovoltaics
Nanotechnology

Background:

Single-molecule electronics require precise measurement techniques.
Understanding charge dynamics in molecular systems is crucial for device applications.

Purpose of the Study:

To investigate the conductance of a porphyrin-fullerene dyad molecule under illumination.
To explore the formation and stability of charge separated states in single molecules.

Main Methods:

Utilized a novel scanning probe microscope stage for break junction measurements.
Performed measurements under visible light illumination and in the dark.
Analyzed molecular layers using transient absorption spectroscopy.

Main Results:

A significant fraction of illuminated molecules exhibited higher conductance.
Conductance decreased in the dark, indicating a reversible process.
Transient absorption spectra supported the formation of a long-lived charge separated state.

Conclusions:

Illumination induces a stable, charge-separated state in the studied molecular system.
The findings have implications for developing efficient molecular photovoltaic devices.