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Updated: Jun 1, 2026
Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
Reversible posterior leukoencephalopathy syndrome after lateral skull base surgery
Isabel Sanchez-Cuadrado1, Luis Lassaletta, Arantxa Royo
1Department of Otolaryngology-Head and Neck Surgery, La Paz University Hospital, Idipaz, Madrid, Spain. iscuadrado@gmail.com
Objective:
To describe the clinical course, diagnostic features and management of a case of reversible posterior leukoencephalopathy syndrome after a lateral cranial base removal.
Patient:
A 58-year-old male patient with an inconspicuous clinical history presented with a lethargic state without localized neurologic deficit in the postoperative period of a subtotal petrosectomy for an adenoid cystic carcinoma of the temporal bone.
Interventions:
Cranial T2-weighted magnetic resonance imaging showed increased signal intensity in the occipital and cerebellar regions, centered at the cortical and subcortical white matter. Antihypertensive drugs, anticonvulsants, and antibiotics were administered. A complete resolution of the symptoms and radiologic findings were achieved within 1 to 2 weeks.
Results:
The clinical presentation, radiologic findings, and resolution of the clinical setting are consistent with a diagnosis of reversible posterior leukoencephalopathy syndrome.
Conclusion:
To our knowledge, this is the first report of reversible posterior leukoencephalopathy syndrome after a lateral cranial base surgery.
