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Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
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Chronic Proliferative Dermatitis in Mice: NFκB Activation Autoinflammatory Disease

Yanhua Liang1

  • 1Department of Dermatology, Yale University School of Medicine, 15 York Street, New Haven, CT 06510, USA.

Pathology Research International
|June 11, 2011
PubMed
Summary

SHARPIN deficient mice exhibit chronic inflammation and epidermal changes, validating the proliferation-inflammation-apoptosis triad in this autoinflammatory disease model. This research offers insights into NFκB activation in congenital inflammatory disorders.

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