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Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
Published on: June 1, 2011
Tetrahedron-structured DNA and functional oligonucleotide for construction of an electrochemical DNA-based biosensor
Nan-Nan Bu1, Chun-Xia Tang, Xi-Wen He
1Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin, 300071, PR China.
Abstract:
Tetrahedron-structured DNA (ts-DNA) in combination with a functionalized oligonucleotide was used to develop a "turn-on" biosensor for Hg(2+) ions. The ts-DNA provided an improved sensitivity and was used to block the active sites.
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