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Updated: Jun 1, 2026
04:23
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
[Perinatal dengue infection]
Griselda Berberian1, Diana Fariña, María Teresa Rosanova
1Hospital Nacional de Pediatría Prof. Dr. Juan P. Garrahan. griselberberian@yahoo.com.ar
Archivos Argentinos De Pediatria
|June 11, 2011
Summary
Dengue, a mosquito-borne viral illness, is spreading in Argentina. This study reviews vertical dengue virus transmission and its impact on newborns, presenting a case of perinatal infection.
Area of Science:
- Medical Entomology
- Infectious Diseases
- Virology
Background:
- Dengue virus (DENV) is transmitted by Aedes aegypti mosquitoes, prevalent in tropical and subtropical regions.
- Argentina eradicated Aedes aegypti in the 1960s but faced vector resurgence in 1984, leading to dengue outbreaks.
- Dengue cases, initially confined to northern provinces, expanded nationwide by the 2008-2009 summer.
Observation:
- Vertical dengue virus transmission, from mother to newborn, is rarely documented.
- The effects of dengue infection on pregnant women and their newborns are not well understood.
- A case of perinatal dengue infection in a newborn from Salta, Argentina, is presented.
Findings:
- This review synthesizes current knowledge on vertical dengue transmission.
- The case study highlights the potential for mother-to-child transmission of dengue virus.
- Perinatal dengue infection presents a significant concern for neonatal health in endemic areas.
Implications:
- Understanding vertical transmission is crucial for preventing neonatal dengue.
- Enhanced surveillance and clinical awareness are needed for pregnant women and newborns in dengue-affected regions.
- Further research is required to elucidate the pathogenesis and clinical outcomes of perinatal dengue infection.
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