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Measurement of rotavirus-neutralizing coproantibody in children by fluorescent focus reduction assay
1Department of Gastroenterology, Royal Children's Hospital, Parkville, Victoria, Australia.
Journal of Clinical Microbiology
|July 1, 1990
Abstract:
A fluorescent focus reduction assay suitable for the measurement of rotavirus-neutralizing antibodies in the feces of children was developed. Of 408 stools tested, 7% showed false-positive neutralization, and the number of rotavirus serotypes neutralized by a fecal extract was proportional to the levels of antirotaviral immunoglobulin A in the extract.