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Curing Methods01:26

Curing Methods

Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...
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Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
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Defining cure.

Paul Hilton1, Dudley Robinson

  • 1Royal Victoria Infirmary, Newcastle upon Tyne, UK. paul.hilton@ncl.ac.uk

Neurourology and Urodynamics
|June 11, 2011
PubMed
Summary
This summary is machine-generated.

This paper explores definitions of 'cure' and 'outcome' in medical research, highlighting how varied definitions impact prevalence studies and cure rates. It discusses subjective versus objective outcomes and their significance for various stakeholders.

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Area of Science:

  • Medical research methodology
  • Clinical trial design

Background:

  • The 2nd Annual meeting of the ICI-Research Society focused on defining 'cure'.
  • Existing definitions of 'cure' and 'outcome' lack standardization.
  • Varying definitions can significantly affect research findings.

Purpose of the Study:

  • To review and discuss various definitions of 'cure' and 'outcome'.
  • To analyze the impact of differing definitions on prevalence studies and cure rates.
  • To explore the significance of subjective versus objective outcomes for different stakeholders.

Main Methods:

  • Review of presentations from a scientific meeting (Proposal 2 - "Defining cure").
  • Discussion of subjective and objective outcome measures.
  • Consideration of patient-reported outcome measures and composite endpoints.

Main Results:

  • Varied definitions of 'cure' and 'outcome' can lead to discrepancies in prevalence and cure rate studies.
  • Subjective and objective outcomes hold different significance for clinicians, patients, carers, and industry.
  • Patient-reported outcome measures and composite endpoints are emerging tools.

Conclusions:

  • Standardized definitions of 'cure' and 'outcome' are crucial for reliable research.
  • Future research should focus on developing and applying validated, patient-centered outcome measures.
  • Clear definitions are essential for accurate interpretation of clinical research and effective patient care.