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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
Diagnosis, prevention and treatment of fungal infections
1St Bartholomew School of Nursing and Midwifery, City University, London. D.Gould@city.ac.uk
Abstract:
Most fungi live harmlessly in the environment, but some species can cause disease in the human host. Nurses working in primary care are likely to see patients with superficial fungal infections and are well placed to offer advice about treatment and measures to prevent the spread of infection in the home. Patients with weakened immune function admitted to hospital are at high risk of developing serious, invasive fungal infections. Systemic fungal infections are a major problem among critically ill patients in acute care settings and are responsible for an increasing proportion of healthcare-associated infections.
Insights
Fungal infections range from superficial to invasive, posing risks to immunocompromised patients in hospitals. Primary care nurses play a key role in managing superficial infections and preventing spread.
Area of Science:
- Mycology
- Infectious Diseases
- Healthcare Epidemiology
Background:
- Fungi are ubiquitous environmental organisms, with some species acting as opportunistic human pathogens.
- Superficial fungal infections are common in primary care settings.
- Invasive and systemic fungal infections represent a significant threat to hospitalized patients, particularly those with compromised immune systems.
Purpose of the Study:
- To highlight the spectrum of fungal infections encountered in healthcare.
- To emphasize the role of primary care nurses in managing superficial fungal infections.
- To underscore the risks and prevalence of invasive fungal infections in acute care settings.
Main Methods:
- Review of current literature on fungal infections.
- Analysis of epidemiological data on healthcare-associated fungal infections.
- Discussion of clinical presentations and management strategies.
Main Results:
- Superficial fungal infections are frequently managed in primary care.
- Immunocompromised patients in hospitals are at high risk for severe fungal infections.
- Systemic fungal infections are an increasing cause of healthcare-associated infections.
Conclusions:
- Nurses in primary care are crucial for early detection and management of superficial fungal infections.
- Vigilance and appropriate interventions are necessary to combat invasive fungal infections in hospitalized patients.
- Addressing the rising incidence of healthcare-associated fungal infections requires a multi-faceted approach.
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