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Updated: Jun 1, 2026
Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging
Published on: December 4, 2016
Preparation and characterization of dendrimer-gold colloid nanocomposites
M E Garcia1, L A Baker, R M Crooks
1Department of Chemistry, Texas A&M University, P.O. Box 30012, College Station, Texas 77842-3012.
Abstract:
Au colloids in the 2-3-nm size regime were prepared by in situ reduction of HAuCl(4) in the presence of poly(amidoamine) dendrimers. The dendrimers encapsulate the colloids, imparting stability to the aqueous colloidal solutions. The nanocomposite materials can be isolated by precipitation. The dendrimer generation used in the synthesis controls the size of the resultant colloids: lower-generation dendrimers give rise to larger colloids. The materials were characterized by infrared and UV-vis spectroscopy and transmission electron microscopy.
