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Updated: Jun 1, 2026
06:27
Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Difficulties in establishing routine amniocentesis for preterm labor evaluation.
Jennifer J McIntosh1, Katherine McHugh, David M Haas
1Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Summary
Implementing amniocentesis for preterm labor (PTL) or preterm premature rupture of membranes (PPROM) showed low uptake. Patient refusal and provider discomfort hindered the procedure
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
Background:
- Preterm labor (PTL) and preterm premature rupture of membranes (PPROM) are significant obstetric concerns.
- Subclinical infection/inflammation evaluation is crucial in managing PTL and PPROM.
Purpose of the Study:
- To assess the real-world implementation and performance of amniocentesis following a practice change for PTL/PPROM evaluation.
- To identify barriers to amniocentesis utilization in this clinical setting.
Main Methods:
- Retrospective review of 59 patients admitted with PTL or PPROM.
- Tracking the offer and performance rates of amniocentesis.
- Analysis of reasons for not performing the procedure.
Main Results:
- Only 23 of 59 patients (39%) were offered amniocentesis.
- Seven patients (30% of those offered) underwent the procedure.
- Overall, only 11.9% of admitted patients received amniocentesis.
Conclusions:
- Implementation of amniocentesis for subclinical infection/inflammation in PTL/PPROM is challenging.
- Patient refusal and provider discomfort were primary barriers to procedure performance.
- Low uptake suggests a need to address implementation strategies and provider training.
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