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Closing the brain-to-brain loop in laboratory testing.

Mario Plebani1, Giuseppe Lippi

  • 1Department of Laboratory Medicine, University-Hospital Padova, Padova, Italy. mario.plebani@unipd.it

Clinical Chemistry and Laboratory Medicine
|June 14, 2011
PubMed
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Improving laboratory services requires understanding the entire "brain-to-brain turnaround time loop." Addressing quality gaps in the extra-analytical phase is crucial for patient safety and effective clinical decisions.

Area of Science:

  • Laboratory Medicine
  • Clinical Pathology
  • Healthcare Quality Improvement

Background:

  • The
  • brain-to-brain turnaround time loop
  • concept highlights laboratory service delivery, including patient action based on results.
  • Systematic feedback for laboratory service improvement is often poorly understood and applied.
  • Lack of quality specifications for the extra-analytical phase hinders budget calculation for patient-related total error.

Purpose of the Study:

  • To emphasize the need for improved quality specifications in the extra-analytical phase of laboratory testing.
  • To advocate for the application of risk management strategies in clinical laboratories.
  • To promote a comprehensive understanding of the total testing process for error reduction.

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Main Methods:

  • Reviewing the historical concept of laboratory service delivery.
  • Analyzing the challenges in defining and applying quality specifications for the extra-analytical phase.
  • Discussing the adoption of risk management strategies like FMEA, FRACAS, LEAN, and Six Sigma.

Main Results:

  • The term
  • total error
  • is often limited to the analytical phase and should be clarified as
  • total analytical error
  • to avoid misinterpretation.
  • The hierarchical approach prioritizes assessing the effect of analytical performance on clinical decisions.
  • Risk management strategies are increasingly adopted to identify critical steps and reduce patient-related errors.

Conclusions:

  • Defining and implementing quality specifications for the extra-analytical phase is essential for improving laboratory services.
  • Adopting risk management strategies aids in identifying critical steps and mitigating patient risk.
  • Monitoring the entire testing process, from test request to result interpretation, is vital for laboratory professionals.