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A Neurite Outgrowth Assay and Neurotoxicity Assessment with Human Neural Progenitor Cell-Derived Neurons
Published on: August 6, 2020
The human brain in a dish: the promise of iPSC-derived neurons
Ricardo Dolmetsch1, Daniel H Geschwind
1Department of Neurobiology, Fairchild Research Building, Room D227, Stanford University, Stanford, CA 94305, USA. ricardo.dolmetsch@stanford.edu
Cell
|June 14, 2011
Abstract:
Induced pluripotent stem cell-derived neurons from patients promise to fill an important niche between studies in humans and model organisms in deciphering mechanisms and identifying therapeutic avenues for neurologic and psychiatric diseases. Recent work begins to tap this potential and also highlights challenges that must be overcome to be fully realized.
