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Periprosthetic joint infection following Staphylococcus aureus bacteremia

Parham Sendi1, Florian Banderet, Peter Graber

  • 1Unit of Infectious Diseases, Basel University Medical Clinic Liestal, Switzerland. sendi-pa@magnet.ch

The Journal of Infection
|June 14, 2011
PubMed
Abstract

Insights

The rate of periprosthetic joint infections (PJI) following Staphylococcus aureus bacteremia (SAB) is high, between 30-40%. This risk is significantly elevated compared to other pathogens, particularly in community-acquired SAB cases.

Area of Science:

  • Orthopedic Surgery
  • Infectious Diseases
  • Epidemiology

Background:

  • Periprosthetic joint infections (PJI) are serious complications after arthroplasty.
  • The incidence of PJI from remote infections is typically low (<1%).
  • Staphylococcus aureus bacteremia (SAB) may pose a higher risk for PJI.

Purpose of the Study:

  • To evaluate the incidence of haematogenous PJI in patients with previously uninfected arthroplasties following SAB.

Main Methods:

  • Retrospective analysis of patients with SAB and prosthetic joints at Basel University Medical Clinic Liestal (1998-2008).

Main Results:

  • 31 patients with 45 prosthetic joints were identified during SAB.
  • SAB led to PJI in 12 patients (39%) and 13 arthroplasties (29%).
  • PJI occurred exclusively in community-acquired SAB (p=0.002), diagnosed within a median of 2.5 days.

Conclusions:

  • The incidence of PJI after SAB is notably high (30-40%), exceeding rates for other bacteremic pathogens.
  • PJI risk is elevated in community-onset SAB, often associated with delayed treatment initiation.

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