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Related Experiment Video

Updated: Jun 1, 2026

Addressing Practical Issues in Atomic Force Microscopy-Based Micro-Indentation on Human Articular Cartilage Explants

Addressing Practical Issues in Atomic Force Microscopy-Based Micro-Indentation on Human Articular Cartilage Explants

Published on: October 28, 2022

Morphologic imaging of articular cartilage.

Colin D Strickland¹, Richard Kijowski

¹Department of Radiology, University of Colorado Denver, Leprino Building, 12401 East 17th Avenue, Mail Stop L954, Aurora, CO 80045, USA. colin.strickland@ucdenver.edu

Magnetic Resonance Imaging Clinics of North America

|June 14, 2011

Summary

Magnetic resonance (MR) imaging is crucial for evaluating articular cartilage. Current MR techniques struggle to detect early cartilage lesions, potentially hindering osteoarthritis diagnosis and treatment.

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Addressing Practical Issues in Atomic Force Microscopy-Based Micro-Indentation on Human Articular Cartilage Explants

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Published on: October 28, 2022

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model

Standardized Histomorphometric Evaluation of Osteoarthritis in a Surgical Mouse Model

Published on: May 6, 2020

Area of Science:

Orthopedics
Radiology
Biomedical Engineering

Background:

Articular cartilage assessment is vital for diagnosing joint diseases.
Magnetic resonance (MR) imaging is a primary tool for cartilage evaluation.
Current MR imaging techniques have limitations in detecting subtle cartilage damage.

Purpose of the Study:

To discuss the role of MR imaging in evaluating articular cartilage.
To describe the appearance of cartilage lesions on MR imaging.
To review current MR imaging techniques for cartilage morphology.

Main Methods:

Review of current literature on MR imaging of articular cartilage.
Discussion of MR imaging sequences and their diagnostic capabilities.
Analysis of limitations in detecting superficial cartilage lesions.

Main Results:

MR imaging is integral to articular cartilage assessment.
Existing MR sequences have limitations in detecting superficial degenerative and posttraumatic cartilage lesions.
These limitations can impede the early diagnosis of osteoarthritis.

Conclusions:

Improved MR imaging techniques are needed for better articular cartilage evaluation.
Enhanced image quality may enable earlier detection of cartilage lesions.
Future advancements could improve the diagnosis and management of osteoarthritis.