Related Experiment Video
Updated: Jun 1, 2026

In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Published on: October 20, 2013
MR imaging assessment of inflammatory, crystalline-induced, and infectious arthritides
Jennifer L Demertzis1, David A Rubin
1Division of Musculoskeletal Radiology, Mallinckrodt Institute of Radiology, 510 South Kingshighway Boulevard, Campus Box 8131, St Louis, MO 63110, USA. demertzisj@mir.wustl.edu
Abstract:
The role of magnetic resonance imaging in evaluating patients with inflammatory arthritides has evolved with the recent introduction of drugs capable of modifying disease activity and natural history. In conditions like rheumatoid arthritis, active synovitis and bone marrow inflammation precede and predict bone and cartilage erosion. These imaging findings identify patients who can be treated early and aggressively to prevent future morbidity. Similarly, in gout and other crystalline disorders, specific diagnosis aided by imaging may lead to earlier medical and surgical management. Infected joints need the most rapid identification to institute immediate therapy and prevent irreversible cartilage destruction.
Related Concept Videos
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Imaging Studies for Cardiovascular System IV: CMRI
Myocarditis II: Clinical Features and Diagnostic Tests
