Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Proofreading01:43

Proofreading

Overview
Proofreading01:31

Proofreading

Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
Errors During Replication are Corrected by the DNA Polymerase Enzyme
Proofreading01:43

Proofreading

Overview
Mutations01:39

Mutations

Overview
Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Mutations01:39

Mutations

Overview

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predictors of COVID-19 vaccination status: a nationwide linkage study in Czechia.

Journal of public health (Oxford, England)·2026
Same author

Cohort profile: The Czech Health, Alcohol and Psychosocial factors In Eastern Europe study (HAPIEE-CZ).

Research square·2026
Same author

Parental alcohol supply in early childhood and adolescent drinking: Evidence from a prospective cohort - ADDENDUM.

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

The impact of place on health: Neighbourhood & residential satisfaction as a contributor to physical and mental health in applicants for publicly subsidized housing.

Health & place·2026
Same author

Parental alcohol supply in early childhood and adolescent drinking: Evidence from a prospective cohort.

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

Income Security Health Promotion: Addressing Patients' Unmet Income Needs in a Toronto Family Practice, a Qualitative Study.

International journal of social determinants of health and health services·2026
Same journal

Comparative social costs of six early years disadvantages: a birth cohort microsimulation study.

Journal of epidemiology and community health·2026
Same journal

Sociodemographic inequalities in non-small cell lung cancer (NSCLC) novel treatments: a national population-based cohort study.

Journal of epidemiology and community health·2026
Same journal

Secular trends in primary care utilisation for mental health problems: a Norwegian register-based population-wide study.

Journal of epidemiology and community health·2026
Same journal

Guide to recent advances in difference-in-differences methodology for population health studies.

Journal of epidemiology and community health·2026
Same journal

From early to fewer first births: ADHD and family formation among young adults.

Journal of epidemiology and community health·2026
Same journal

10-year mortality among first-time mothers involved in family court care proceedings in England: cohort study using linked administrative hospital, mortality and family court records.

Journal of epidemiology and community health·2026
See all related articles

Related Experiment Video

Updated: Jun 1, 2026

Microinjection for Transgenesis and Genome Editing in Threespine Sticklebacks
08:51

Microinjection for Transgenesis and Genome Editing in Threespine Sticklebacks

Published on: May 13, 2016

Editorial changes at JECH

James R Dunn, Martin Bobak

    Journal of Epidemiology and Community Health
    |June 14, 2011
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    New Features in Visual Dynamics 3.0
    05:00

    New Features in Visual Dynamics 3.0

    Published on: August 9, 2024

    Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs)
    09:11

    Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs)

    Published on: June 14, 2012

    Related Experiment Videos

    Last Updated: Jun 1, 2026

    Microinjection for Transgenesis and Genome Editing in Threespine Sticklebacks
    08:51

    Microinjection for Transgenesis and Genome Editing in Threespine Sticklebacks

    Published on: May 13, 2016

    New Features in Visual Dynamics 3.0
    05:00

    New Features in Visual Dynamics 3.0

    Published on: August 9, 2024

    Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs)
    09:11

    Genome Editing with CompoZr Custom Zinc Finger Nucleases (ZFNs)

    Published on: June 14, 2012