Related Experiment Video
Updated: Jun 1, 2026

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
Published on: April 30, 2021
Systems modeling in integrative oncology
Brian D Lawenda1, Sanford A Friedenthal, Stephen M Sagar
121st Century Oncology, Las Vegas, NV 89109, USA. blawenda@rtsx.com
The Integrative Oncology Systems Model (IOSM) offers a unified approach to analyze cancer data. This systems modeling framework evaluates interventions and behavior changes impacting cancer progression and patient outcomes.
Area of Science:
- Systems biology
- Computational oncology
- Health informatics
Background:
- Systems modeling integrates diverse data for comprehensive analysis.
- Understanding cancer requires analyzing multidisciplinary factors.
Purpose of the Study:
- Introduce the Integrative Oncology Systems Model (IOSM).
- Assess the impact of interventions and behavior modification on cancer.
- Evaluate effects on survival and quality of life.
Main Methods:
- Utilizing a systems modeling framework.
- Integrating multidisciplinary data streams.
- Standardized data analysis for cancer research.
Main Results:
- The IOSM facilitates assessment of therapeutic interventions.
- Behavior modification impacts on cancer progression can be evaluated.
- The model links interventions to survival and quality of life outcomes.
Conclusions:
- The IOSM provides an integrated approach to oncology systems modeling.
- This model aids in predicting outcomes of interventions and behavior changes.
- IOSM supports personalized medicine and treatment optimization.
More Related Videos
Related Concept Videos
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Mouse Models of Cancer Study
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Pharmacodynamic Models: Overview
Cancer Survival Analysis

