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Updated: Jun 1, 2026
08:32
Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Enterococcus avium bacteremia: a 12-year clinical experience with 53 patients
1Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 86, Asanbyeongwon-gil, Songpa-gu, Seoul, 138-736, Republic of Korea.
Summary
Enterococcus avium bacteremia, often originating from biliary or abdominal infections, presents a significant mortality risk. Inadequate antimicrobial therapy and severe underlying conditions independently increase patient mortality.
Area of Science:
- Infectious Diseases
- Clinical Microbiology
- Epidemiology
Background:
- Enterococcus avium bacteremia is infrequently reported, with limited understanding of its clinical manifestations and patient outcomes.
- Formerly known as "group Q streptococcus," E. avium's role in bloodstream infections requires further investigation.
Purpose of the Study:
- To retrospectively analyze the clinical features and outcomes of patients experiencing Enterococcus avium bacteremia.
- To identify risk factors associated with mortality in E. avium bacteremia.
Main Methods:
- Retrospective evaluation of 53 patients with E. avium bacteremia at a tertiary-care hospital in Korea (1997-2009).
- Data collected included infection source, polymicrobial status, nosocomial acquisition, vancomycin resistance, and mortality rates.
- Multivariate analysis was employed to determine independent risk factors for mortality.
Main Results:
- E. avium bacteremia commonly arose from biliary (50.9%) or intra-abdominal (24.5%) sources, frequently in polymicrobial settings (67.9%).
- Nosocomial bloodstream infections accounted for 62.3% of cases; no vancomycin resistance was observed.
- Crude mortality was 24.5%, with an E. avium bacteremia-related mortality of 11.3%.
Conclusions:
- Enterococcus avium bacteremia is often linked to biliary/intra-abdominal infections and polymicrobial bacteremia, carrying a considerable crude mortality rate.
- Severe underlying disease and inadequate antimicrobial therapy were identified as significant independent risk factors for mortality in E. avium bacteremia patients.
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