Related Experiment Video
Updated: Jun 1, 2026

11:17
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Complex medicines management.
1NHS Milton Keynes.
Summary
A joint medication management project for patients with long-term conditions (LTCs) improved care quality and safety. This initiative reduced emergency visits and hospital admissions, leading to significant cost savings.
Area of Science:
- Healthcare Management
- Clinical Pharmacy
- Patient Safety
Background:
- Patients with long-term conditions (LTCs) frequently manage multiple prescribed medications.
- Polypharmacy in LTCs poses challenges to medication adherence and safety.
- A need for coordinated medication services in primary care was identified.
Purpose of the Study:
- To describe the implementation and outcomes of a joint medication management project.
- To evaluate the impact of a holistic, collaborative approach to medication management.
- To assess improvements in quality, safety, and cost-effectiveness for LTC patients.
Main Methods:
- A collaborative project involving a specialist nurse and pharmacist was established.
- A holistic approach was adopted to manage medications for patients with LTCs.
- The project focused on coordinating medication services within a primary care setting.
Main Results:
- The one-year project demonstrated improvements in medication management quality and patient safety.
- Significant reductions were observed in out-of-hours patient presentations.
- Hospital admissions related to medication issues were decreased, alongside cost reductions.
Conclusions:
- Joint medication management projects can enhance patient safety and care quality for LTC populations.
- Collaborative pharmaceutical and nursing interventions are effective in optimizing medication use.
- Integrated medication management strategies can lead to reduced healthcare utilization and costs.
Related Concept Videos
Therapeutic Drug Monitoring: Affecting Factors
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
Therapeutic Drug Monitoring: Overview and Classification
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
Methods of Documentation VI: Case Management Model
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic illness...
For example, a patient with a chronic illness...
Drug Classes and Categories
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
Therapeutic Drug Monitoring: Drug Analysis Methods
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
Drug Therapy
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
