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Updated: Jun 1, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Basal plus basal-bolus approach in type 2 diabetes.

F Javier Ampudia-Blasco¹, Paolo Rossetti, Juan F Ascaso

¹Diabetes Reference Unit, Endocrinology and Nutrition Department, Clinic University Hospital of Valencia, Valencia, Spain. Francisco.J.Ampudia@uv.es

Diabetes Technology & Therapeutics

|June 15, 2011

Summary

For type 2 diabetes patients needing insulin, the basal plus strategy offers an alternative to premixed insulin. This approach intensifies basal insulin with prandial injections, progressing to basal-bolus therapy if needed.

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Last Updated: Jun 1, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Area of Science:

Endocrinology
Metabolic Diseases
Pharmacology

Background:

Type 2 diabetes involves insulin resistance and beta-cell decline, often necessitating insulin therapy.
Oral diabetes medications may eventually be insufficient, requiring insulin initiation.
Basal insulin is a common starting point, but some patients need further intensification.

Purpose of the Study:

To review evidence for the basal plus strategy in type 2 diabetes management.
To discuss the progression from basal plus to basal-bolus therapy.
To provide practical guidance for initiating and adjusting basal plus therapy.

Main Methods:

Review of current evidence on basal plus and basal-bolus insulin strategies.
Analysis of treatment intensification pathways for type 2 diabetes.
Discussion of practical recommendations for insulin therapy adjustment.

Main Results:

Basal insulin addition is a simple starting point for insulin therapy.
Basal plus strategy involves adding prandial insulin to basal insulin.
Basal-bolus therapy remains the most effective for hyperglycemia reduction in type 2 diabetes.

Conclusions:

The basal plus strategy is an alternative to premixed insulin, managing postprandial glucose.
Progression to basal-bolus therapy is a viable intensification option.
Effective titration and adjustment are key for successful basal plus therapy.