Related Experiment Video
Updated: Jun 1, 2026

A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
Sesamoid disorders of the first metatarsophalangeal joint
Allan Boike1, Molly Schnirring-Judge, Sean McMillin
1Foot and Ankle Center, Orthopaedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Abstract:
The sesamoid complex is located centrally and plantar to the first metatarsal head, where they are imbedded within the plantar plate, which transmits 50% of body weight and more than 300% during push-off, is susceptible to numerous pathologies. These pathologies include sesamoiditis, stress fracture, avascular necrosis, osteochondral fractures, and chondromalacia, and are secondary to these large weight-bearing loads. This article discusses sesamoid conditions and their relationship with hallux limitus, and reviews the conditions that predispose the first metatarsophalangeal joint to osteoarthritic changes.
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