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Immunohistochemical study of IOT-10 natural killer cells in brain metastases
J Vaquero1, S Coca, J Escandón
1Department of Neurosurgery, Puerta de Hierro Clinic, Autonomous University, Madrid, Spain.
Acta Neurochirurgica
|January 1, 1990
Abstract:
The presence of NK-cells in a series of 40 metastatic brain tumours has been studied by means of the monoclonal antibody IOT-10. There appeared IOT-10 NK-cells in all tumours studied, but in most cases these cells represented less than 10% of the tumour infiltrating lymphocytes (TIL). In the present series, the obtained data suggest that the number of NK-cells in brain metastases can be influenced by other factors than the mere quantity of TIL.