Intraocular pressure response to selective laser trabeculoplasty in the first treated eye vs the fellow eye

To determine if the intraocular pressure (IOP) response to selective laser trabeculoplasty (SLT) in one eye predicts long-term response to SLT in the fellow eye.

A retrospective medical record review was performed of patients who underwent SLT as primary treatment in both eyes and who completed at least 30 months of follow-up visits. Pearson product moment correlation analysis was performed to determine correlations between the 3-month percentage of IOP reduction in the first treated eye and long-term percentages of IOP reduction in the fellow eye.

Medical records of 80 eyes in 40 patients were reviewed. In patients with ocular hypertension, the 3-month percentage of IOP reduction in the first treated eye correlated strongly with long-term percentages of IOP reduction in the fellow eye (r > 0.652). In patients with primary open-angle glaucoma, the 3-month percentage of IOP reduction in the first treated eye correlated moderately with percentages of IOP reduction in the fellow eye up to 9 months (r > 0.367).

In patients with ocular hypertension, the 3-month percentage of IOP reduction in the first treated eye in response to SLT was predictive of response in the fellow eye up to 30 months. In patients with primary open-angle glaucoma, the 3-month percentage of IOP reduction in the first treated eye in response to SLT was predictive of response in the fellow eye up to 9 months.