Related Experiment Video
Updated: Jan 9, 2026

Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
Published on: July 20, 2022
Demystifying ventricular assist devices
1Allegheny General Hospital/WPAHS, Pittsburgh, Pennsylvania 15212, USA. KLITTON@wpahs.org
Insights
Ventricular assist devices (VADs) offer life-saving cardiac support for heart failure patients awaiting transplants or as long-term therapy. Technological advancements have improved VADs, enabling many to live quality lives.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Devices
Background:
- Heart disease and advanced heart failure affect millions globally.
- Limited donor hearts necessitate alternative treatments for heart transplantation.
- Mechanical circulatory support devices have emerged as a viable option.
Purpose of the Study:
- To discuss the evolution and current state of ventricular assist devices (VADs).
- To highlight VADs as a critical alternative for patients with advanced heart failure.
- To review five prominent types of left ventricular assist devices.
Main Methods:
- Review of VAD technology development over the past 30 years.
- Categorization of VADs into generations (e.g., pulsatile flow vs. axial/rotary pumps).
- Discussion of VADs used as bridge-to-transplant and destination therapy.
Main Results:
- VAD technology has progressed from large pulsatile devices to smaller, more efficient axial flow or rotary pumps.
- Improvements in device size, driveline, battery life, and device longevity have enhanced patient outcomes.
- Thousands of individuals with implanted VADs are experiencing improved quality of life and functional capacity.
Conclusions:
- Ventricular assist devices (VADs) represent significant advancements in managing advanced heart failure.
- Modern VADs offer improved performance and longevity, supporting patients awaiting transplants or as permanent solutions.
- Continued innovation in VAD technology is crucial for expanding treatment options for heart disease patients.
Abstract:
Many people throughout the world are living with heart disease and advanced heart failure. They may be in need of a heart transplant, but because of the limited amount of donor hearts available, other options need to be available. Because of the advancement of technology, there are now other options, and one option available would be a mechanical circulatory and cardiac support device. Ventricular assist devices (VADs) have been developed over the past 30 years. From larger, earlier pulsatile devices to smaller, hand-held, newer axial flow or rotary pump devices, VADs are implanted cardiac assist devices. They are implanted to provide cardiac support and can be used temporarily as a bridge to transplant (for those awaiting a heart transplant) or implanted permanently, which is known as destination therapy. With the changes in the size of device, decrease in the size of drive line, increased length of battery life, as well as length of device life, thousands of people now have these implanted VAD devices and are living quality lives and functioning at high levels. Currently, there are 3 generations of the left ventricular assist devices being used throughout the world. Five of the most well-known type of left ventricular assist devices are discussed in this article.
Related Concept Videos
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy II: Dilated Cardiomyopathy
Heart Failure VI: Adjunct Therapies
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...

