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Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus
Published on: September 5, 2013
Methicillin-resistant Staphylococcus lugdunensis carrying SCCmec type V misidentified as MRSA
Eliezer Menezes Pereira1, Ricardo Pinto Schuenck, Simone Aranha Nouér
1Applied Microbiology and Fermentation Processes Laboratory, Instituto Federal de Educação, Ciência e Tecnologia do Rio de Janeiro, RJ, Brazil.
Abstract:
Staphylococcus lugdunensis is a rare cause of severe infections and clinical manifestations are similar to those related to S. aureus infection. We describe a hospital-acquired bacteremia due to methicillin-resistant Staphylococcus lugdunensis, misidentified as methicillin-resistant S. aureus. The oxacillin MIC was 16 µg/mL and the mecA gene and SCCmec type V were determined by PCR. Although treatment had been appropriated, the patient died after rapid progressive respiratory failure and another nosocomial sepsis. It is important not only to identify S. lugdunensis in view of its clinical course, but also to determine its susceptibility to oxacillin by detecting the mecA gene or its product.
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