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Published on: December 2, 2017
[Research progress on living quality of children conceived by assisted reproductive technology]
1Centre of Reproductive Medicine, Women's Hospital, College of Medicine Zhejiang University, Hangzhou 310006, China.
Insights
Assisted reproductive technique (ART) safety is crucial as more children are born via ART. This review examines ART
Area of Science:
- Reproductive Medicine
- Pediatric Health
- Public Health
Context:
- Assisted reproductive technique (ART) is increasingly utilized globally.
- Children born following ART represent a significant population subgroup.
- Assessing the long-term health and safety of ART-conceived children is a growing concern.
Purpose:
- To review the current understanding of health issues in children conceived via ART.
- To consolidate data on perinatal outcomes and short-term follow-up studies.
- To identify areas for future research on ART safety and child well-being.
Summary:
- ART-conceived children face potential risks including multiple pregnancies, low birth weight, prematurity, congenital anomalies, and imprinting disorders.
- Neurodevelopmental outcomes, neonatal health, physical and mental well-being, and cancer risks require ongoing monitoring.
- This review synthesizes existing data on these health concerns to inform further investigation.
Impact:
- Provides a comprehensive overview of health considerations for ART-conceived children.
- Highlights the need for continued surveillance and research into ART safety.
- Informs clinical practice and public health policy related to assisted reproduction.
Abstract:
With the development of assisted reproductive technique (ART), children born following ART now form a sizeable subgroup of the population, so assessment for the safety of ART becomes more urgent than ever before. The health problems about living quality of children conceived by ART mainly focus on perinatal outcome and short-term follow-up study, including multiple pregnancies, low birth weight and prematurity in singleton births, congenital malformations, imprinting disorders, neurodevelopmental outcome, neonatal outcomes, physical and mental health, as well as cancer risks. In this review, we will discuss the health problems of these children, to provide data for further study.
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