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Updated: Jun 1, 2026

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A Simplified Technique for Producing an Ischemic Wound Model
Published on: May 2, 2012
A simple method of earlobe lesion excision and repair
Samuel J Fishpool1, Mohamed M Abo-Khatwa, Jonathan E Osborne
1Department of Otolaryngology-Head and Neck Surgery, Glan Clwyd Hospital, Bodelwyddan, Denbighshire, UK.
Ear, Nose, & Throat Journal
|June 16, 2011
Abstract
No abstract available in PubMed .
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Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...

