Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longevity and Volume Expansion of Hyaluronic Acid Dermal Fillers: A Cross-sectional 3-dimensional Magnetic Resonance Imaging Study.

Plastic and reconstructive surgery. Global open·2026
Same author

A Brush With Danger: A Case Report of a Toothbrush Impalement Injury to the Oral Cavity.

Case reports in dentistry·2026
Same author

Radiological Features of Human Papillomavirus (HPV)-Positive and HPV-Negative Oropharyngeal Squamous Cell Carcinoma (OPSCC)-Considerations for Multimodal Analysis.

Cancers·2026
Same author

Clinical Presentation and Tumour Burden in Head and Neck Sarcomas: Implications for Early Diagnosis and Referral.

Cancers·2026
Same author

Optical Coherence Tomography Assessment of Tongue Papillary Atrophy and Patient-Reported Impact on Taste Following Head and Neck Cancer Therapy.

Journal of clinical medicine·2026
Same author

Optical Coherence Tomography for Invasive Oral Squamous Cell Carcinoma: Diagnostic Accuracy and Grade- and Subsite-Associated Imaging Features.

Journal of clinical medicine·2026

Related Experiment Video

Updated: Jun 1, 2026

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
13:48

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

Interstitial PDT for vascular anomalies.

Waseem Jerjes1, Tahwinder Upile, Zaid Hamdoon

  • 1UCLH Head and Neck Centre, London, United Kingdom. waseem_wk1@yahoo.co.uk

Lasers in Surgery and Medicine
|June 16, 2011
PubMed
Summary

Interstitial photodynamic therapy (PDT) offers a successful treatment for vascular anomalies, improving quality of life and reducing symptoms like pain and bleeding. This approach is effective for conditions resistant to conventional therapies.

More Related Videos

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
09:31

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

Published on: January 27, 2023

Related Experiment Videos

Last Updated: Jun 1, 2026

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
13:48

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

Published on: April 21, 2023

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
09:31

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

Published on: January 27, 2023

Area of Science:

  • Vascular Surgery
  • Oncology
  • Dermatology

Background:

  • Photodynamic therapy (PDT) is an established treatment for various conditions.
  • Vascular anomalies present complex management challenges, often requiring innovative therapeutic strategies.

Purpose of the Study:

  • To prospectively evaluate the outcomes of interstitial photodynamic therapy (PDT) in patients with head and neck vascular anomalies.
  • To assess the impact of PDT on patients' quality of life, clinical presentation, and radiological findings.

Main Methods:

  • Forty-three patients with diverse vascular anomalies received interstitial PDT using mTHPC.
  • Treatment involved general anaesthesia and a photosensitizing agent.
  • Patients were followed up for a mean of 21 months, with clinical, radiological, and quality-of-life assessments.

Main Results:

  • Significant improvements were reported in pain (15/19), bleeding (7/8), swelling (28/35), infection episodes (8/11), and disfigurement (31/36).
  • Functional improvements included reduced swallowing (9/12) and breathing problems (7/9).
  • Clinical assessment revealed a 'good response' in 50% of patients, with moderate responses in 30.2%; radiological assessment showed moderate to significant responses in over 60% of patients.

Conclusions:

  • Interstitial PDT is an effective treatment for vascular anomalies, particularly those resistant to conventional therapies.
  • The modality demonstrates a favorable safety profile with minimal side effects.
  • PDT significantly enhances patient quality of life by alleviating symptoms and improving functional outcomes.