Related Experiment Video
Updated: Jun 1, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
[Controversies regarding the pathogenesis of cardiovascular diseases in HIV patients]
S Barelli1, A Angelillo-Scherrer, A Kenfak Foguena
1Service et laboratoire central d'hématologie, CHUV et Université de Lausanne. stefano.barelli@chuv.ch
Controversies regarding the pathogenesis of cardiovascular diseases in HIV patients Since the introduction of HAART (Highly active anti-retroviral therapy), the incidence of cardiovascular events has risen in patients infected with HIV. This development is mainly due to the increased survival in these patients. Nonetheless, the pathogenic effects of HIV on the principal components of haemostasis (endothelium, platelets and the clotting cascade) are the subject of numerous ongoing research studies, and are becoming an argument for starting HAART or for modifying the components of an established therapy. The aim of this article is to raise clinician awareness regarding the issue of cardiovascular disease in the HIV-infected patient.
Controversies regarding the pathogenesis of cardiovascular diseases in HIV patients Since the introduction of HAART (Highly active anti-retroviral therapy), the incidence of cardiovascular events has risen in patients infected with HIV. This development is mainly due to the increased survival in these patients. Nonetheless, the pathogenic effects of HIV on the principal components of haemostasis (endothelium, platelets and the clotting cascade) are the subject of numerous ongoing research studies, and are becoming an argument for starting HAART or for modifying the components of an established therapy. The aim of this article is to raise clinician awareness regarding the issue of cardiovascular disease in the HIV-infected patient.
Related Concept Videos
Coronary Artery Disease II: Pathophysiology
Sexually Transmitted Infections
Coronary Artery Disease III: Clinical Manifestations
Pathophysiology of Cardiac Performance
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
