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Related Concept Videos

Visual Agnosia01:12

Visual Agnosia

Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round end"...
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Learning Disabilities

Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
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Language and Cognition01:27

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
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Negative and Cognitive Symptoms of Schizophrenia

Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
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Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...

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Related Experiment Video

Updated: Jun 1, 2026

Lexical Decision Task for Studying Written Word Recognition in Adults with and without Dementia or Mild Cognitive Impairment
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Alexia without agraphia.

E Mulroy1, S Murphy, T Lynch

  • 1Dublin Neurological institute, Mater Misericordiae University Hospital, Eccles St, Dublin 7. eoinmulroy@gmail.com

Irish Medical Journal
|June 17, 2011
PubMed
Summary
This summary is machine-generated.

Alexia without agraphia, a disconnection syndrome, occurs when the brain hemispheres are disconnected. This case report details a patient with pure alexia caused by an embolic left occipital lobe infarct.

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Area of Science:

  • Neuroscience
  • Neurology
  • Clinical Neurology

Background:

  • Alexia without agraphia, or pure alexia, is a rare neurological condition characterized by the inability to read despite preserved writing ability.
  • It is considered a disconnection syndrome, resulting from damage to the communication pathways between cerebral hemispheres.
  • Historically, Déjerine first described this syndrome in 1892 following a left occipital lobe infarct.

Observation:

  • This report presents a case of a patient who developed alexia without agraphia.
  • The patient's condition resulted from an embolic infarct affecting the left occipital lobe.
  • The infarct extended to involve the posterior commissure and the splenium of the corpus callosum.

Findings:

  • The patient exhibited symptoms consistent with alexia without agraphia.
  • Neuroimaging confirmed an embolic infarct in the left occipital lobe, impacting critical white matter tracts.
  • The lesion's specific location, including the posterior commissure and splenium, provides insight into the disconnection mechanism.

Implications:

  • This case reinforces the understanding of alexia without agraphia as a disconnection syndrome.
  • It highlights the crucial role of the splenium of the corpus callosum and posterior commissure in visual word processing.
  • Further research into lesion-symptom mapping in pure alexia can refine diagnostic and therapeutic strategies.