Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 1, 2026

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury
06:31

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury

Published on: October 6, 2020

[Histological study on sciatic nerve repair at different angles in rats].

Xiaofeng Chu1, Hongjiang Ruan, Junjian Liu

  • 1Department of Orthopaedics, Weihaiwei People's Hospital, Weihai Shandong, 264200, PR China.

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi = Zhongguo Xiufu Chongjian Waike Zazhi = Chinese Journal of Reparative and Reconstructive Surgery
|June 17, 2011
PubMed
Summary

Sciatic nerve repair at 30-45 degrees significantly improves neural regeneration in rats compared to steeper angles. Optimal repair angles promote better nerve recovery and function.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sodium butyrate induces cuproptosis by regulating the HDAC1-SLC31A1 axis in hepatocellular carcinoma.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association·2026
Same author

An implantable mechano-electro cascade platform synchronizes neuro-muscle repair.

Nature communications·2026
Same author

Aryl hydrocarbon receptor: a multifaceted environmental sensor in liver homeostasis and disease.

Frontiers in medicine·2026
Same author

Injectable chitosan-based hydrogel via in situ gelation modulates the inflammatory microenvironment and facilitates minimally invasive repair of peripheral nerve injury.

Materials today. Bio·2026
Same author

HR-Mamba: Building Footprint Segmentation with Geometry-Driven Boundary Regularization.

Sensors (Basel, Switzerland)·2026
Same author

Infrared land surface emissivity dynamics in the Taklimakan desert from 2001 to 2023.

Scientific reports·2026

Area of Science:

  • Neuroscience
  • Regenerative Medicine
  • Surgical Innovation

Context:

  • Peripheral nerve injuries, such as sciatic nerve transection, present significant challenges in achieving functional recovery.
  • Understanding the impact of surgical technique on nerve regeneration is crucial for improving clinical outcomes.

Purpose:

  • To investigate the influence of different sciatic nerve repair angles on the process of neural regeneration in a rat model.
  • To determine the optimal angle for end-to-end neurorrhaphy to promote effective sciatic nerve repair.

Summary:

  • This study evaluated sciatic nerve regeneration in rats following transection and repair at angles of 30, 45, 60, and 90 degrees.
  • Regeneration was assessed through morphological, histological, and functional analyses at 1, 2, and 3 months post-operation.

More Related Videos

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
04:34

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Published on: January 25, 2022

Related Experiment Videos

Last Updated: Jun 1, 2026

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury
06:31

Automated Gait Analysis to Assess Functional Recovery in Rodents with Peripheral Nerve or Spinal Cord Contusion Injury

Published on: October 6, 2020

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
04:34

Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice

Published on: January 25, 2022

  • Results indicated that repair angles of 30-45 degrees yielded significantly better outcomes in terms of muscle weight recovery, nerve conduction velocity, and axonal regeneration compared to 60-90 degrees.

    • Impact:

    • The findings suggest that precise angulation during sciatic nerve repair is a critical factor in enhancing nerve regeneration.
    • This research provides valuable insights for surgical techniques aimed at optimizing functional recovery after peripheral nerve injuries.