Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Biofiltration without buffering substances in the dialysate].

F Quarello¹, R Boero, G Martina

¹Università di Torino, Istituto di Nefro-Urologia.

Minerva Urologica E Nefrologica = the Italian Journal of Urology and Nephrology

|January 1, 1990

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effects of supplementation of sea buckthorn press cake on mycelium growth and polysaccharides of Inonotus obliquus in submerged cultivation.

Journal of applied microbiology·2021

Same author

[Effects of dose of erythropoiesis stimulating agents on cardiovascular outcomes, quality of life and costs of haemodialysis. the clinical evaluation of the DOSe of erythropoietins (C.E. DOSE) Trial].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2013

Same author

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits.

Journal of animal physiology and animal nutrition·2013

Same author

[Vascular access in elderly: AVF versus CVC].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2008

Same author

[How to start dialysis. Peritoneal dialysis--clinical aspects].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia·2008

Same author

Control of inflammation and prophylaxis of endophthalmitis after cataract surgery: a multicenter study.

European journal of ophthalmology·2007

Same journal

Trimodal therapy in muscle invasive bladder cancer management.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020

Same journal

Is androgen deprivation therapy protective against SARS-CoV-2 infection and related complications in prostate cancer patients?

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020

Same journal

Bowel suture technique for bladder neck reconstruction during RALP and its impact on early continence recovery.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020

Same journal

Systematic review of neoadjuvant therapy by immune checkpoint inhibitors before radical cystectomy: where do we stand?

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020

Same journal

Functional and oncological outcomes of 3D clampless sutureless laparoscopic partial nephrectomy for renal tumors with low nephrometry score.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020

Same journal

Robot-assisted laparoscopic pyeloplasty in children: a systematic review.

Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2020

See all related articles

Acetate-free biofiltration (AFB) effectively corrects uremic acidosis and offers good hemodynamic tolerance in patients with chronic kidney disease. This safe and feasible hemodiafiltration technique is a competitive alternative to existing treatments.

Area of Science:

Nephrology
Biomedical Engineering

Context:

Chronic uremia treatment often involves managing metabolic acidosis and hemodynamic instability.
Existing hemodiafiltration techniques may have limitations in acid-base balance control.

Purpose:

To evaluate the efficacy and safety of acetate-free biofiltration (AFB) in treating chronic uremia.
To assess the acid-base balance and hemodynamic tolerance of AFB.

Summary:

Acetate-free biofiltration (AFB) utilizes a buffer-free dialysate with post-dilution sodium bicarbonate infusion.
Acute studies show stable pCO2, with significant inverse correlation between bicarbonate changes and basal levels, correcting uremic acidosis without alkalosis.
Long-term follow-up in 6 patients over 31 months demonstrates AFB's feasibility, safety, and good hemodynamic tolerance.

Related Experiment Videos

Impact:

AFB provides effective correction of uremic acidosis and excellent hemodynamic stability.
It presents a competitive alternative to bicarbonate hemodialysis, hemodiafiltration, and standard biofiltration.
This technique offers a promising option for improving the quality of life for patients with chronic kidney disease.