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Related Experiment Video

Updated: May 31, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

Reninoma presenting as cardiac syncope.

Shahid I Tak¹, Mohd Lateef Wani, Khursheed A Khan

¹Department of Cardiology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, India.

Annals of Pediatric Cardiology

|June 17, 2011

Summary

This summary is machine-generated.

Reninoma, a rare kidney tumor, can cause secondary hypertension in children. This case highlights a renin-secreting tumor presenting as cardiac syncope due to hypokalemia.

Keywords:

Hypokalemia reninoma secondary hypertension

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Novel Approach for Simultaneous Recording of Renal Sympathetic Nerve Activity and Blood Pressure with Intravenous Infusion in Conscious, Unrestrained Mice.

Novel Approach for Simultaneous Recording of Renal Sympathetic Nerve Activity and Blood Pressure with Intravenous Infusion in Conscious, Unrestrained Mice.

Published on: February 14, 2018

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Last Updated: May 31, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion

Published on: May 26, 2022

Novel Approach for Simultaneous Recording of Renal Sympathetic Nerve Activity and Blood Pressure with Intravenous Infusion in Conscious, Unrestrained Mice.

Novel Approach for Simultaneous Recording of Renal Sympathetic Nerve Activity and Blood Pressure with Intravenous Infusion in Conscious, Unrestrained Mice.

Published on: February 14, 2018

Area of Science:

Pediatric Endocrinology
Nephrology
Cardiology

Background:

Reninoma is a rare, surgically curable cause of secondary hypertension in pediatric patients.
Juxtaglomerular cell tumors can secrete excess renin, leading to elevated blood pressure.

Observation:

A pediatric case presented with cardiac syncope, an unusual manifestation.
Electrocardiogram revealed a prolonged QTc interval, indicative of cardiac electrical instability.

Findings:

The cardiac syncope and prolonged QTc were attributed to severe hypokalemia.
The hypokalemia was a consequence of excessive renin secretion from a reninoma.

Implications:

This case underscores the importance of considering reninoma in children with unexplained hypertension and hypokalemia.
Early diagnosis and surgical treatment of reninoma can prevent serious cardiac complications.
Highlights the link between endocrine tumors, electrolyte imbalances, and cardiac events in pediatrics.