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Oropharyngeal Crohn's disease
Rachid Mohamed1, Robert Schultz, Richard N Fedorak
1Division of Gastroenterology, University of Alberta, Edmonton, Alberta.
Clinical and Experimental Gastroenterology
|June 17, 2011
Summary
This case report highlights a rare presentation of Crohn's disease (CD) affecting the oropharynx, causing painful swallowing. Diagnosis was confirmed through investigations revealing both ileal and oropharyngeal ulcers.
Area of Science:
- Gastroenterology
- Internal Medicine
- Otorhinolaryngology
Background:
- Crohn's disease (CD) is a chronic inflammatory condition typically affecting the gastrointestinal tract, commonly presenting with abdominal pain and diarrhea.
- Oropharyngeal involvement in Crohn's disease is infrequent, often presenting with non-specific symptoms that can delay diagnosis.
Purpose of the Study:
- To describe a unique case of Crohn's disease presenting with odynophagia (painful swallowing) due to an oropharyngeal ulcer.
- To review existing literature on oropharyngeal Crohn's disease and discuss management strategies.
Main Methods:
- Case report detailing a 38-year-old female patient with new-onset odynophagia.
- Clinical examination, endoscopic visualization of the oropharynx and ileum, and hemoglobin level assessment.
- Literature review of previously reported cases and treatment options for oropharyngeal Crohn's disease.
Main Results:
- Direct visualization revealed a large, serpiginous ulcer in the oropharynx.
- Gastroenterologic investigations confirmed concurrent ileal Crohn's disease and identified the oropharyngeal ulcer as a manifestation of the disease.
- Patient experienced a significant drop in hemoglobin levels, indicating potential gastrointestinal bleeding.
Conclusions:
- Oropharyngeal Crohn's disease can present atypically with odynophagia, necessitating thorough investigation.
- Early recognition and diagnosis of oropharyngeal Crohn's are crucial for effective management and preventing complications.
- This case underscores the importance of considering Crohn's disease in the differential diagnosis of unexplained oropharyngeal ulcers.
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