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Updated: May 31, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
[Biphosphonate-induced femoral stress fractures : A new problem and knowledge so far - case report]
R Lenz1, M Ellenrieder, R Skripitz
1Orthopädische Klinik und Poliklinik, Universitätsklinikum Rostock, Doberanerstr. 142, 18057, Rostock, Deutschland. robert.lenz@med.uni-rostock.de
Abstract:
During the last several years the treatment of osteoporosis with bisphosphonates has become accepted as a safe and effective procedure. However, recently there have been increasing numbers of reports of rare complications in the literature. Particularly the occurrence of atypical fractures of the femur has become a focus of interest but the problem is insufficiently known and only rarely addressed in the scientific discussion. The case illustrated here and a survey of the important facts in the recent literature highlight essential aspects of long-term bisphosphonate therapy.
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