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Updated: May 31, 2026

Brain Banking: Making the Most of your Research Specimens
Published on: July 24, 2009
Descartins, the memory molecules
1Psychology Department and Beckman Institute, University of Illinois at Urbana-Champaign, USA. i-weiler@uiuc.edu
Abstract:
Investigation of protein translation at the synapse, using functioning synaptic particles termed synaptoneurosomes, has led to identification of Fragile X protein as a key synaptic component. In its absence, some key mRNAs are translated more diffusely in the cell, and more slowly. Recent studies have implicated ERK (extracellular receptor regulated kinase) as a central factor in regulating the kinetics of translation at the synapse.
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