Related Experiment Video
Updated: May 31, 2026

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device
Published on: August 30, 2016
[The human microbiome]
Ido Solt1, Matthew J Kim, Cohavy Offer
1Maternal-Fetal Medicine Division, Obstetrics and Gynecology Department Cedars-Sinai Medical Center, Los Angeles, CA, USA. soliti@cshs.org
Abstract:
The complex microbial populations that colonize the human body form the human microbiome. The human microbiota may contain 1014) cells, an order of magnitude greater than the number of the human cells, and can express 100 times more genes than the human genome. The metagenome is the collective genomes of the human and its microbial flora. Major international colLaborative efforts currently explore the diverse human microbiomes from five different body areas: the nasopharyngeal, gastrointestinal and female urogenital tracts, the oral cavity and the skin. Defining the complexity of the human microbiome in health and disease will enhance the understanding of multiple pathological mechanisms and facilitate the development of novel diagnostic tools and therapeutic interventions.
Related Concept Videos
Introduction to the Human Microbiota
Development of Human Microbiota
Microbiota of the Large Intestine
The Skin Microbiota
Functions of the Gut Microbiota
The Oral Microbiota

