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Motor delay in cystic fibrosis infants: an observational study

Paula de Almeida Thomazinho1, Célia Regina Moutinho de Miranda Chaves, Caroline Pinto Pássaro

  • 1Pediatrics Department, Instituto Fernandes Figueira/FIOCRUZ, Rio de Janeiro, Brazil. pthomazinho@iff.fiocruz.br

Early Human Development
|June 18, 2011
PubMed

Insights

A significant number of children with cystic fibrosis (CF) experience delayed gross motor development. Factors like low stature and prolonged hospital stays are linked to these early motor deficits in CF patients.

Area of Science:

  • Pediatric Medicine
  • Developmental Pediatrics
  • Genetics

Background:

  • Cystic Fibrosis (CF) is a genetic disorder affecting multiple organs.
  • Early detection of developmental delays is crucial for intervention in CF patients.

Purpose of the Study:

  • To determine the prevalence of delayed gross motor development in infants and toddlers with CF.
  • To identify potential risk factors associated with motor delays in this population.

Main Methods:

  • A cross-sectional observational study included 15 children aged 6-42 months with CF.
  • Data collected included demographics, anthropometrics, clinical characteristics, and Shwachman scores.
  • Motor abilities were assessed using the Bayley Scales of Infant and Toddler Development® - III Edition (BSITD-III).

Main Results:

  • Motor development delay was identified in 26.7% of the children studied.
  • Statistically significant associations were found between motor delay and low stature, low weight, and prolonged hospitalizations (>60 days).
  • In 75% of affected children, significant differences existed between gross and fine motor scores.

Conclusions:

  • The high prevalence of motor delay suggests that biological and environmental factors in CF contribute to early motor deficits.
  • Monitoring motor development is essential for timely and adequate intervention in children with CF.
Abstract

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