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Updated: May 31, 2026

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Isolation of Circulating Tumor Cells in an Orthotopic Mouse Model of Colorectal Cancer
Published on: July 18, 2017
Disseminated and circulating tumor cells in gastrointestinal oncology
F C Bidard1, F R Ferrand, F Huguet
1Department of Medical Oncology, Institut Curie, Paris, France. fcbidard@curie.fr
Critical Reviews in Oncology/Hematology
|June 18, 2011
Abstract:
Circulating (CTCs) and disseminated tumor cells (DTCs) are two different steps in the metastatic process. Several recent techniques have allowed detection of these cells in patients, and have generated many results using different isolation techniques in small cohorts. Herein, we review the detection results and their clinical consequence in esophageal, gastric, pancreatic, colorectal, and liver carcinomas, and discuss their possible applications as new biomarkers.

