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Updated: May 31, 2026
12:22
A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
Published on: April 2, 2012
Mollaret's meningitis and herpes simplex virus type 2 infections
P Farazmand1, P D Woolley, G R Kinghorn
1Sexual Health Department, South Manchester University Hospitals, Manchester, UK. pfarazmand@googlemail.com
International Journal of STD & AIDS
|June 18, 2011
Summary
Benign recurrent aseptic meningitis, a rare disorder, is now linked to the herpes simplex type 2 virus. Antiviral therapies show success in preventing and treating this condition.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Benign recurrent aseptic meningitis (BRM) is a rare neurological disorder.
- Initially described by Mollaret in 1944, the cause was unknown.
- Advances in diagnostics have identified specific causative agents.
Purpose of the Study:
- To identify the causative agent of benign recurrent aseptic meningitis.
- To evaluate the efficacy of antiviral treatment for BRM.
Main Methods:
- Review of diagnostic tools for aseptic meningitis.
- Identification of viral agents in patient samples.
- Analysis of treatment outcomes with antiviral medications.
Main Results:
- Herpes simplex virus type 2 (HSV-2) identified as the most common agent.
- Successful prophylaxis and treatment of BRM using antiviral agents.
Conclusions:
- Herpes simplex virus type 2 is a primary cause of benign recurrent aseptic meningitis.
- Antiviral treatment is effective for managing BRM.
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