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Updated: May 31, 2026

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
Venous thrombosis in children: an emerging issue
Angelo C Molinari1, Paola Saracco, Valerio Cecinati
1Dipartimento di Emato Oncologia, Istituto Giannina Gaslini, Genoa, Italy.
Pediatric venous thrombosis is increasingly diagnosed due to advanced imaging and central venous catheters. This review guides physicians in managing pediatric thrombosis, including diagnosis, treatment, and prophylaxis.
Area of Science:
- Pediatric Hematology
- Vascular Medicine
- Critical Care Medicine
Background:
- Increased diagnosis of pediatric venous thrombosis linked to advanced imaging and central venous catheters.
- Longer survival for children with critical conditions increases thrombosis risk.
- Existing guidelines for pediatric thrombosis treatment are available but often require individualized anticoagulant therapy.
Purpose of the Study:
- To equip physicians with essential background information for managing pediatric thrombosis.
- To aid in the detection and diagnosis of thrombotic events in children.
- To provide guidance on risk stratification, prophylaxis, and pharmacologic treatment strategies.
Main Methods:
- Review of current literature and clinical guidelines on pediatric venous thrombosis.
- Analysis of factors contributing to increased thrombotic events in children.
- Discussion of diagnostic approaches and treatment recommendations.
Main Results:
- Newer imaging modalities enhance the detection of venous thrombosis in pediatric patients.
- Central venous catheters are a significant factor in the rise of thrombotic events.
- Limited clinical data exists for newer antithrombotic drugs in pediatric populations.
Conclusions:
- Physicians need comprehensive information to effectively manage pediatric thrombosis.
- Early detection, appropriate testing, and guideline-based treatment are crucial.
- Understanding high-risk populations and future pharmacologic options is vital for prophylaxis and treatment.
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