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[Calcitonin gene products and the skeleton]
1Forschungslabor für Calciumstoffwechsel, Orthopädischen Universitätsklinik Balgrist.
Zeitschrift Fur Orthopadie Und Ihre Grenzgebiete
|May 1, 1990
Abstract:
Calcitonin is the most important hypocalcaemic peptide. Its action is brought about through inhibition of bone resorption. CGRP exerts the same effect on the skeleton albeit in much higher concentrations probably through interaction with calcitonin receptors on osteoclasts. PAS-57 stimulates the incorporation of thymidine into osteoblasts. A possible stimulation of bone formation needs to be verified in vivo.