Related Experiment Video
Updated: May 31, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Community-associated methicillin-resistant Staphylococcus aureus causing orbital cellulitis in Australian children
Vikram L Vaska1, Keith Grimwood, Glen A Gole
1The University of Queensland, UQ Centre for Clinical Research, Herston, QLD, Australia. v.vaska@uq.edu.au
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is a growing cause of severe eye infections. In Australia, CA-MRSA has rapidly become a leading cause of orbital cellulitis in children since 2009.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) as a significant pathogen.
- Increasing global incidence of serious ocular infections attributed to CA-MRSA.
- Need for understanding the epidemiology of CA-MRSA in pediatric populations.
Observation:
- First documented case of CA-MRSA orbital cellulitis at a tertiary pediatric hospital in Brisbane, Australia in 2009.
- Subsequent identification of CA-MRSA as a causative agent in a notable proportion of orbital cellulitis cases.
- The pathogen has been implicated in 4 out of 9 recorded orbital cellulitis infections since its initial detection.
Findings:
- CA-MRSA has rapidly emerged as a key pathogen in pediatric orbital cellulitis.
- The incidence of CA-MRSA-related orbital infections has increased significantly since 2009.
- A substantial percentage of orbital cellulitis cases in this cohort are now linked to CA-MRSA.
Implications:
- Highlights the importance of considering CA-MRSA in the differential diagnosis of pediatric orbital cellulitis.
- Suggests a potential shift in the microbial landscape of ocular infections.
- Underscores the need for enhanced surveillance and timely management strategies for CA-MRSA eye infections in children.
Related Concept Videos
Staphylococcal Skin Infections
Clinical Significance of Antibiotic Resistance
Mechanism of Antibiotic Resistance in MRSA
Bacterial Meningitis I: Introduction
Bacterial Meningitis
Microbiome of the Eye
