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Updated: May 31, 2026

Preoxygenation Techniques for Tracheal Intubation in Critically Ill Adults Utilizing Oxygen Mask and Noninvasive Ventilation
Published on: December 5, 2025
Portable pulse-dose oxygen concentrators should not be used with noninvasive ventilation
Salvador Díaz Lobato1, Esteban Pérez Rodríguez, Sagrario Mayoralas Alises
1Pneumological Department, Hospital Ramón y Cajal de Madrid, Madrid, Spain. sdiazlobato@gmail.com
Portable oxygen concentrators are not suitable for use with nocturnal noninvasive ventilation (NIV). Testing revealed they fail to detect patient breathing or deliver adequate oxygen during NIV therapy.
Area of Science:
- Respiratory Medicine
- Biomedical Engineering
Background:
- Home oxygen therapy and noninvasive ventilation (NIV) are increasingly used together, particularly by COPD and overlap-syndrome patients.
- Stationary oxygen concentrators are the usual oxygen source for nocturnal NIV.
Observation:
- A patient used a portable oxygen concentrator with nocturnal NIV without medical guidance.
- The study evaluated the portable oxygen concentrator's performance under various connection points and NIV settings.
Findings:
- The portable oxygen concentrator failed to detect inspiratory effort during NIV across all tested settings.
- Adequate oxygen flow delivery was not achieved with the portable oxygen concentrator during simulated NIV.
Implications:
- Portable oxygen concentrators are not recommended for concurrent use with nocturnal NIV.
- This finding is crucial for patient safety and effective respiratory support management.
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